Most polyps are cholesterol polyps, but some may be adenomatous. Less than 0.5% of adenomatous polyps are malignant, and neoplasms usually occur only in polyps larger than 10 mm; therefore, patients with polyps 10 mm or greater should be referred for cholecystectomy. If polyps are less than 10 mm in size but are symptomatic, cholecystectomy is also indicated.

Ultrasonography in 6 months could be considered for a patient with an asymptomatic polyp 6 to 9 mm in size with no other risk factors.

Ultrasonography in 1 year should be performed for a patient with a polyp 5 mm or smaller in size and no other risk factors.

ACP MKSAP